The comparing of acute effects of two training models aerobic and resistance on the clotting times in young women students

Keywords: clotting time, exercise training, PT, aPTT, young women students, blood, coagulation factor

Abstract

Purpose: Some of the benefits of physical activity may result from effects on hemostasis. However, the increased burden of cardiovascular complications and sudden death occurring during and immediately after exercise prompts investigation to elucidate the biological relationship between physical exercise and hemostatic function. The aim of this study was to determine effects of one bout exhaustive aerobic exercise and resistance training on the clotting times in healthy young women student. Material: Thirty trained volunteer female students of physical education were selected objectively and availability. The subjects were randomly divided into two groups of aerobic (n=15) and resistance training (n=15). Aerobic group performed exhaustive workout program on treadmill intensity 65 to75% VO2max on treadmill. The resistance group completed three sets of 5-7 repetitions of six exercises at an intensity corresponding to 80% of 1RM. Following 12 to 14 hours of nightly fasting, venous blood samples (5 cc) were collected pre, immediately after exercise and after 60 min of recovery and analyzed for PT (Prothrombin Time) and aPTT (Activated Partial Thromboplastin Time) times. Participants were matched according to anthropometric measurements, age and VO2max. Hypothesizes were tested by using independent t, repeated measures and post-hoc test (p≤0.05). Results: One bout of the exhaustive aerobic exercise and resistance training caused significantly shortening in PT (p<0.001) and aPTT (p=0.006, p<0.001 respectively) times at immediately after exercise. Also aPTT (p=0.005, p<0.001 respectively) times significantly increased after recovery in comparison with baseline levels in two groups. No significantly differences observed in PT and aPTT between two groups in all stages. The results show that exhaustive aerobic exercise and resistance training lead to mild and transit increase in coagulation system and induced shortening clotting times. Exercise-related hypercoagulability is mainly due to an increase in coagulation factor VIII (FVIII) with no parallel alterations of other clotting factors. Conclusions: Similar to endurance exercise, FVIII activity raises following resistance exercise, and appears to be positively correlated with the volume of weight lifted. The ß-adrenergic pathway has been implicated as a possible pathway mediating an exercise- induced increase in FVIII and decease clotting time.

Downloads

Download data is not yet available.

| Abstract views: 390 | PDF Downloads: 303 |

Author Biographies

M. Rahmani Ghobadi, Islamic Azad University
mrahmani.uni@gmail.com; Moalem Square, Islamic Azad University, Damavand, Tehran Province, Iran
M. Forghani Ozrudi, Islamic Azad University
mohammadbagher.forghani@gmail.com; Mazandaran province, Babol City, Education office, Department of physical education, Babol, Iran

References

1. El-Sayed MS, El-Sayed Z, Aahmadizad A. Exercise and Training Effects o blood Heamostasis in Health and Disease. Sport Med, 2004;34(3): 181-200.
https://doi.org/10.2165/00007256-200434030-00004

2. Wang JS. Exercise prescription and thronbogenesis. Biochem Sci, 2006;13(2): 753-751.
https://doi.org/10.1007/s11373-006-9105-7

3. Lippi G, Maffulli N. Biological influence of physical exercise on hemostasis. Semin Thromb Hemost, 2009;35(3): 269-76.
https://doi.org/10.1055/s-0029-1222605

4. Habibi M, Torkaman G, Goosheh B, Hedayati M. The effect of combined resistance-aerobic and aerobic training on the coagulative factors of young healthy men. Physiol Pharmacol. 2009; 13 (1):98-107.

5. Menzel, K, Hilberg T. Coagulation and fibrinolysis are in balance after moderate exercise in middle-aged participants. Clinical and Applied Thrombosis/Hemostasis, 2009;15(3):348-355.
https://doi.org/10.1177/1076029608326306

6. Lekakis J, Triantafyllidi H, Galea V. The immediate effect of aerobic exercise on haemostatic parameters in patients with recently diagnosed mild to moderate essential hypertension. G Thromb Thrombolysis, 2008;25(2): 179-84.
https://doi.org/10.1007/s11239-007-0058-0

7. Hilberg T, Glaser D, Reskhart C, Prasa D, Sturzebecher J, Gabriel HH. Blood coagulation and fibrinolysis after long-duration treadmill exercise controlled by individual anaerobic threshold. Eur J Appl Physiol, 2003;90: 639-642.
https://doi.org/10.1007/s00421-003-0907-2

8. Nagelkirk PR, Scalzo R, Harber M, Kaminsky LA. The influence of acute Resistance Training and body composition on coagulation and fibrinolytic activity in low risk women. Int G spoets med, 2010;31(7): 458-462.
https://doi.org/10.1055/s-0030-1249623

9. Rezaiean Z, Torkaman G, Nadali F. Effect of physical fitness on the coagulate activity of healthy young men. Pak J Biol Sci, 2006;9(11): 2032-203.
https://doi.org/10.3923/pjbs.2006.2032.2039

10. Boldt LH, Fraszl W, Röcker L, Schefold JC, Steinach M, Noack T, Gunga HC. Changes in the haemostatic system after thermoneutral and hyperthermic water immersion. European journal of applied physiology, 2008;102(5): 547-554.
https://doi.org/10.1007/s00421-007-0620-7

11. Hilberg T, Eichler E, Glaser D. Blood coagulation and fibrinolysis before and after exhaustive exercise in patients with IDDM. Thromb Haemosd, 2003;90(6): 1065-73.

12. Picciome Fazio GF, Giudice E. Exercise induced change in clotting times and fibrinolytic activity during official 1600 and 2000 meters’ trot races in standard bred horses. Acta Vet Brno, 2005;74(3): 509-514.
https://doi.org/10.2754/avb200574040509

13. Hilberg TG, Glaser D, Prasa D. Pure eccentric exercise does not activate blood coagulation. European journal of applied physiology, 2005;94(5-6): 718-721.
https://doi.org/10.1007/s00421-005-1353-0

14. Madarame H, Kurano M, Takano H, Lida H, Sato Y, Ohshima H. Effect of low-intensity resistance exercise with blood flow restriction on coagulation system in healthy subjects. Clinical physiology and functional imaging, 2010;30(3): 210-213.
https://doi.org/10.1111/j.1475-097X.2010.00927.x

15. Ahmadizad S, El-Sayed M. The acute effects of resistance exercise on the main determinants of blood rheology. Journal of Sports sciences, 2005;23(3): 243-249.
https://doi.org/10.1080/02640410410001730151
Published
2019-08-28
How to Cite
1.
Rahmani Ghobadi M, Forghani Ozrudi M. The comparing of acute effects of two training models aerobic and resistance on the clotting times in young women students. Physical education of students. 2019;23(4):198-01. https://doi.org/10.15561/20755279.2019.0406
Section
Articles