THE EFFECT OF SLEEP DEPRIVATION ON SERUM IGG RESPONSES TO AEROBIC ACTIVITY IN COLLEGE STUDENT ATHLETES
DOI:
https://doi.org/10.15561/20755279.2014.0617Keywords:
sleep, deprivation, Immune, IgGAbstract
Background & Aims: Sleep is a restorative process for the immune system. There are many situations in which sleep is disturbed prior to an athletic event. However, the effect of sleep deprivation on immune indices in response to exercise remains unknown. The aim of this study was to investigate the effects of sleep deprivation on serum IgG responses to aerobic activity. Materials & Methods: In this quasi-experimental study, 10 male physical education students were voluntarily participated. Study was performed in two separate occasions; control and experimental within two weeks. In the control occasion, normal sleep and aerobic activity and in the experimental occasion, sleep deprivation and aerobic activity was applied. Aerobic activity was performed on bicycle ergometer for 30 minutes at intensity of 70 to 75 percent of maximum heart rate. Changes in serum IgG concentrations in pre-test, before and after aerobic activity in both occasions were analyzed by the two repeated measures ANOVA and dependent T-test using SPSS software. Results: The results showed that sleep deprivation not significantly effect on Serum IgG response to aerobic activity (p=0.130). Also, aerobic activity not significantly effect on Serum IgG concentration (p=0.357). But sleep deprivation caused a significantly increase in serum IgG concentration (p=0.035). Conclusion: No significant effect of sleep deprivation on serum IgG concentrations response to aerobic activity.Downloads
Download data is not yet available.
References
<p>Akerstedt T. <i>Shift work and disturbed sleep/wakefulness</i>. Sleep Med Rev. 1998, vol 2, pp.117–128.</p>
<p>Bentivoglio M., Kristensson K. Neural–immune interactions in disorders of sleep-wakefulness organization.<i> Trends Neurosci</i>. 2007, vol 30, pp. 645–52.</p>
<p>Born J., Lange T., Hansen K., Mölle M., Fehm H.L. Effects of sleep and circadian rhythm on human circulating immune cells. <i>Journal of</i><em>Immunology</em>. 1997, vol.158, pp. 4454-4464.</p>
<p>Boyum A., Wiik P., Gustavsson E., Veiby O. P., Reseland J., Haugen A. H., Opstad P. K. The effect of strenuous exercise, calorie deficiency and sleep deprivation on white blood cells, plasma immunoglobulins and cytokines. <em>Scandinavian</em> <i>Journal of</i> <em>Immunology</em>. 1996, vol.43, pp. 228–235.</p>
<p>Bryant P.A., Trinder J., Curtis N. Sick and tired: Does sleep have a vital role in the immune system? <i>Nature Reviews Immunology</i>. 2004, vol.4, pp. 457-467.</p>
<p>Cohen S., Doyle W.J., Alper C.M., Janicki-Deverts D., Turner R.B. Sleep habits and susceptibility to the common cold. <i>Archives of Internal Medicine</i>. 2009, vol.169, pp. 62-67.</p>
<p>Dinges D.F., Douglas S.D., Hamarman S., Zaugg L., Kapoor S. Sleep deprivation and human immune function. <i>Advances in</i> <em>Neuroimmunology</em>. 1995, vol.5, pp. 97-110.</p>
<p>Fondell E., Axelsson J., Franck K., Ploner A., Lekander M. Short natural sleep is associated with higher T cell and lower NK cell activities. <em>BrainBehavior</em> <i>and</i> <em>Immunity</em>. 2011, vol.25, pp. 1367-75.</p>
<p>Gleeson M. Immune functions in sport and exercise. <em>Journal</em> <i>of Applied Physiology</i>. 2007, vol.10, pp. 693–699.</p>
<p>Gunga H.C., Machotta A., Schobersberger W., Mittermayr M., Kirsch K., Koralewski E. Neopterin, IgG, IgA, IgM, and Plasma Volume Changes During Long-distance Running<b>. </b><i>Pteridines. </i>2002, vol.13, pp. 13-20.</p>
<p>Harma M., Hakola T., Kandolin I., Sallinen M., Virkkala J., Bonnefond A. A controlled intervention study on the effects of a very rapidly forward rotating shift system on sleep– wakefulness and well-being among young and elderly shift workers.<i> <em>International Journal of Psychophysiology</em></i>. 2006, vol.59, pp. 70–79.</p>
<p>Heiser P., Dickhaus B., Schreiber W., Clement H.W., Hasse C. White blood cells and cortisol after sleep deprivation and recovery sleep in humans. <em>European</em> <i>Archives</i> <i>of</i> <em>Psychiatry</em> <i>and Clinical</i> <em>Neuroscience</em>. 2000, vol.25, pp. 16-23.</p>
<p>Hui L., Hua F., Diandong H., Hong Y. Effects of sleep and sleep deprivation on immunoglobulins and complement in humans. <em>Brain</em> <em>Behavior</em> <i>and</i><em>Immunity</em>. 2007, vol.21, pp. 308–310.</p>
<p>Irwin M., McClintick J., Costlow C., Fortner M., White J. Partial night sleep deprivation reduces natural killer and cellular immune responses in humans. <i>FASEB Journal.</i> 1996, vol.10, pp. 643-653.</p>
<p>Irwin M. Immune correlates of depression. <i>Advances in Experimental</i> <em>Medicine</em> <i>and</i> <em>Biology</em>. 1999, vol.46, pp. 1–24.</p>
<p>Israel S., Buhl B., Neumann G. Die konzentration der immunoglobulin A, G und M im serum bei trainierten und untrainierten sowie nach verschiedenen sportlicken ausdauerleistungen. <em>Sports Medicine</em> <i>(Berlin).</i> 1982, vol.22, pp. 225–231.</p>
<p>Jurkowski M.K., Bobek-Billewicz B. Influence of sleep deprivation on immunity<i>. Studies in Ethnicity and Nationalism</i>. 2002, vol.2, pp. 95–98.</p>
<p>Karacabey K., Peker I., Saygm O., Ciloglu F., Ozmerdivenli R., Bulut V. Effects of Acute Aerobic and Anaerobic Exercise on Humoral Immune Factors in Elite Athletes. <i>Biotechnology & Biotechnological Equipment</i>. 2005, vol.19, pp. 175-180.</p>
<p>Karacabey K., Saygin O., Ozmerdivenli R., Zorba E., Godekmerdan A., Bulut V. The effects of exercise on the immune system and stress hormones in sportwomen. <i>Neuroendocrinology Letters</i>. 2005, vol.26, pp. 361-366.</p>
<p>Killgore W.D., Killgore D.B., Day L.M. The effects of 53 hours of sleep deprivation on moral judgment. <i>Sleep</i>. 2007, vol.30, pp. 345-352.</p>
<p>Kwarecki K., Zużewicz K. Patterns of sleep and locomotor activity in shift workers with special reference to night shift.<i> Medycyna pracy</i>. 2002, vol.53, pp. 79–84.</p>
<p>Lim J., Dinges D.F. Sleep deprivation and vigilant attention. <em>Annals</em> <i>of the</i> <em>New York Academy</em> <i>of Sciences.</i> 2008, vol.29, pp. 305-322.</p>
<p>Mackinnon L.T., Hooper S.L. Mucosal (secretory) immune system responses to exercise of varying intensity and during overtraining. <em>International Journal of Sports Medicine</em>. 1994, vol.15, pp. 179–183.</p>
<p>Mashiko T., Umeda T., Nakaji S. Effects of exercise on the physical condition of college rugby players during summer training camp. <i>British Journal of Sports Medicine.</i> 2004, vol.38, pp. 186–190.</p>
<p>Mackinnon L.T. Immunoglobulin, antibody, and exercise. <em>Exercise Immunology</em> <i>Review.</i> 1996; vol.35, pp. 21–35.</p>
<p>Mashiko T., Umeda T., Nakaji S. Effects of exercise on the physical condition of college rugby players during summer exercise camp. <i>British Journal of Sports Medicine.</i> 2004, vol.38, pp. 186–190.</p>
<p>Moldofsky H, Lue FA, Davidson JR, Gorczynski R. Effects of sleep deprivation on human immune functions. <i>FASEB</i> <em>Journal</em>. 1989, vol.3, pp. 1972-1977.</p>
<p>Monk T.H., Welsh D.K. The role of chronobiology in sleep disorders medicine. <em>Sleep Medicine</em> <i>Reviews.</i> 2003, vol.7, pp. 455–473.</p>
<p>Mullington J.M., Simpson N.S., Meier-Ewert H.K., Haack M. Sleep loss and inflammation. <em>Best Practice</em> & <i>Research Clinical</i> <em>Endocrinology</em> & <em>Metabolism</em>. 2010, vol.24, pp. 775-784.</p>
<p>Nehlsen-Cannarella S.L., Nieman D.C., Jessen J. The effects of acute moderate exercise on lymphocyte function and serum immunoglobulin levels. <em>International Journal of Sports Medicine</em>. 1991, vol.12, pp. 391–398.</p>
<p>Gunga H-C., Machotta A., Schobersberger W. Neopterin, IgG, IgA, IgM, and Plasma Volume Changes During Long-distance Running. <i>Pteridines.</i>2002, vol.13, pp.13-20. <a href="http://dx.doi.org/10.1515/pteridines.2002.13.1.15">doi:10.1515/pteridines.2002.13.1.15</a></p>
<p>Nieman D., Miller A., Henson D., Warren B., Gusewitch G., Johnson R. Effects of high- vs moderateintensity exercise on natural killer cell activity. <em>Medicine</em> & <em>Science</em> <i>in</i> <em>Sports</em> & <em>Exercise</em>. 1993, vol.25, pp. 1126–1134.</p>
<p>Nieman D.C., Tan S.A., Lee J.W. Complement and immunoglobulin levels in athletes and sedentary controls. <em>International Journal of Sports Medicine. </em>1989, vol.10, pp. 124–128.</p>
<p>Nieman D.C., Nehlsen-Cannarella S.L. The effects of acute and chronic exercise and immunoglobulins. <em>Sports Medicine. </em>1991, vol.11, pp. 183–201.</p>
<p>Oztürk L., Pelin Z., Karadeniz D., Kaynak H., Cakar L. Effects of 48 hours sleep deprivation on human immune profile. <em>Sleep Research,</em> 1999, vol.2, pp. 107-111.</p>
<p>Petibois C., Cazorla G., Deleris G. The biological and metabolic adaptations to 12 months training in elite rowers. <em>International Journal of Sports Medicine. </em>2003, vol.24, pp. 36–42.</p>
<p>Poortmans J., Haralambie G. Biochemical changes in a 100 km run: proteins in serum and urine. <em>European</em> <i>Journal of</i> <em>Physiology</em>, 1979, vol.40, pp. 245–254.</p>
<p>Renwine L., Hauger R.L., Gilln J.C., Irwin M. Effects of sleep and sleep deprivation on interleukin-6, growth hormone, cortisol, and melatonin levels in humans. <i>Journal of Clinical</i> <em>Endocrinology</em> & <em>Metabolism. </em>2000, vol.85, pp. 3597–3603.</p>
<p>Ruiz F.S., Andersen M.L., Martins R.C., Zager A., Lopes J.D., Tufik S. Immune alterations after selective rapid eye movement or total sleep deprivation in healthy male volunteers. <em>Innate Immunity.</em> 2012, vol.18, pp. 44-54.</p>
<p>Taheri M., Arabamery M. The effect of sleep deprivation on choice reaction time and anaerobic power of college student athletes. <i>Asian Journal of Sports Medicine</i>, 2012, vol.3, pp. 15-20.</p>
<p>Tamagawa R., Lobb B., Booth R. Tolerance of shift work. <i>Applied</i> <em>Ergonomics.</em> 2007, vol.38, pp. 635–642.</p>
<p>Bentivoglio M., Kristensson K. Neural–immune interactions in disorders of sleep-wakefulness organization.<i> Trends Neurosci</i>. 2007, vol 30, pp. 645–52.</p>
<p>Born J., Lange T., Hansen K., Mölle M., Fehm H.L. Effects of sleep and circadian rhythm on human circulating immune cells. <i>Journal of</i><em>Immunology</em>. 1997, vol.158, pp. 4454-4464.</p>
<p>Boyum A., Wiik P., Gustavsson E., Veiby O. P., Reseland J., Haugen A. H., Opstad P. K. The effect of strenuous exercise, calorie deficiency and sleep deprivation on white blood cells, plasma immunoglobulins and cytokines. <em>Scandinavian</em> <i>Journal of</i> <em>Immunology</em>. 1996, vol.43, pp. 228–235.</p>
<p>Bryant P.A., Trinder J., Curtis N. Sick and tired: Does sleep have a vital role in the immune system? <i>Nature Reviews Immunology</i>. 2004, vol.4, pp. 457-467.</p>
<p>Cohen S., Doyle W.J., Alper C.M., Janicki-Deverts D., Turner R.B. Sleep habits and susceptibility to the common cold. <i>Archives of Internal Medicine</i>. 2009, vol.169, pp. 62-67.</p>
<p>Dinges D.F., Douglas S.D., Hamarman S., Zaugg L., Kapoor S. Sleep deprivation and human immune function. <i>Advances in</i> <em>Neuroimmunology</em>. 1995, vol.5, pp. 97-110.</p>
<p>Fondell E., Axelsson J., Franck K., Ploner A., Lekander M. Short natural sleep is associated with higher T cell and lower NK cell activities. <em>BrainBehavior</em> <i>and</i> <em>Immunity</em>. 2011, vol.25, pp. 1367-75.</p>
<p>Gleeson M. Immune functions in sport and exercise. <em>Journal</em> <i>of Applied Physiology</i>. 2007, vol.10, pp. 693–699.</p>
<p>Gunga H.C., Machotta A., Schobersberger W., Mittermayr M., Kirsch K., Koralewski E. Neopterin, IgG, IgA, IgM, and Plasma Volume Changes During Long-distance Running<b>. </b><i>Pteridines. </i>2002, vol.13, pp. 13-20.</p>
<p>Harma M., Hakola T., Kandolin I., Sallinen M., Virkkala J., Bonnefond A. A controlled intervention study on the effects of a very rapidly forward rotating shift system on sleep– wakefulness and well-being among young and elderly shift workers.<i> <em>International Journal of Psychophysiology</em></i>. 2006, vol.59, pp. 70–79.</p>
<p>Heiser P., Dickhaus B., Schreiber W., Clement H.W., Hasse C. White blood cells and cortisol after sleep deprivation and recovery sleep in humans. <em>European</em> <i>Archives</i> <i>of</i> <em>Psychiatry</em> <i>and Clinical</i> <em>Neuroscience</em>. 2000, vol.25, pp. 16-23.</p>
<p>Hui L., Hua F., Diandong H., Hong Y. Effects of sleep and sleep deprivation on immunoglobulins and complement in humans. <em>Brain</em> <em>Behavior</em> <i>and</i><em>Immunity</em>. 2007, vol.21, pp. 308–310.</p>
<p>Irwin M., McClintick J., Costlow C., Fortner M., White J. Partial night sleep deprivation reduces natural killer and cellular immune responses in humans. <i>FASEB Journal.</i> 1996, vol.10, pp. 643-653.</p>
<p>Irwin M. Immune correlates of depression. <i>Advances in Experimental</i> <em>Medicine</em> <i>and</i> <em>Biology</em>. 1999, vol.46, pp. 1–24.</p>
<p>Israel S., Buhl B., Neumann G. Die konzentration der immunoglobulin A, G und M im serum bei trainierten und untrainierten sowie nach verschiedenen sportlicken ausdauerleistungen. <em>Sports Medicine</em> <i>(Berlin).</i> 1982, vol.22, pp. 225–231.</p>
<p>Jurkowski M.K., Bobek-Billewicz B. Influence of sleep deprivation on immunity<i>. Studies in Ethnicity and Nationalism</i>. 2002, vol.2, pp. 95–98.</p>
<p>Karacabey K., Peker I., Saygm O., Ciloglu F., Ozmerdivenli R., Bulut V. Effects of Acute Aerobic and Anaerobic Exercise on Humoral Immune Factors in Elite Athletes. <i>Biotechnology & Biotechnological Equipment</i>. 2005, vol.19, pp. 175-180.</p>
<p>Karacabey K., Saygin O., Ozmerdivenli R., Zorba E., Godekmerdan A., Bulut V. The effects of exercise on the immune system and stress hormones in sportwomen. <i>Neuroendocrinology Letters</i>. 2005, vol.26, pp. 361-366.</p>
<p>Killgore W.D., Killgore D.B., Day L.M. The effects of 53 hours of sleep deprivation on moral judgment. <i>Sleep</i>. 2007, vol.30, pp. 345-352.</p>
<p>Kwarecki K., Zużewicz K. Patterns of sleep and locomotor activity in shift workers with special reference to night shift.<i> Medycyna pracy</i>. 2002, vol.53, pp. 79–84.</p>
<p>Lim J., Dinges D.F. Sleep deprivation and vigilant attention. <em>Annals</em> <i>of the</i> <em>New York Academy</em> <i>of Sciences.</i> 2008, vol.29, pp. 305-322.</p>
<p>Mackinnon L.T., Hooper S.L. Mucosal (secretory) immune system responses to exercise of varying intensity and during overtraining. <em>International Journal of Sports Medicine</em>. 1994, vol.15, pp. 179–183.</p>
<p>Mashiko T., Umeda T., Nakaji S. Effects of exercise on the physical condition of college rugby players during summer training camp. <i>British Journal of Sports Medicine.</i> 2004, vol.38, pp. 186–190.</p>
<p>Mackinnon L.T. Immunoglobulin, antibody, and exercise. <em>Exercise Immunology</em> <i>Review.</i> 1996; vol.35, pp. 21–35.</p>
<p>Mashiko T., Umeda T., Nakaji S. Effects of exercise on the physical condition of college rugby players during summer exercise camp. <i>British Journal of Sports Medicine.</i> 2004, vol.38, pp. 186–190.</p>
<p>Moldofsky H, Lue FA, Davidson JR, Gorczynski R. Effects of sleep deprivation on human immune functions. <i>FASEB</i> <em>Journal</em>. 1989, vol.3, pp. 1972-1977.</p>
<p>Monk T.H., Welsh D.K. The role of chronobiology in sleep disorders medicine. <em>Sleep Medicine</em> <i>Reviews.</i> 2003, vol.7, pp. 455–473.</p>
<p>Mullington J.M., Simpson N.S., Meier-Ewert H.K., Haack M. Sleep loss and inflammation. <em>Best Practice</em> & <i>Research Clinical</i> <em>Endocrinology</em> & <em>Metabolism</em>. 2010, vol.24, pp. 775-784.</p>
<p>Nehlsen-Cannarella S.L., Nieman D.C., Jessen J. The effects of acute moderate exercise on lymphocyte function and serum immunoglobulin levels. <em>International Journal of Sports Medicine</em>. 1991, vol.12, pp. 391–398.</p>
<p>Gunga H-C., Machotta A., Schobersberger W. Neopterin, IgG, IgA, IgM, and Plasma Volume Changes During Long-distance Running. <i>Pteridines.</i>2002, vol.13, pp.13-20. <a href="http://dx.doi.org/10.1515/pteridines.2002.13.1.15">doi:10.1515/pteridines.2002.13.1.15</a></p>
<p>Nieman D., Miller A., Henson D., Warren B., Gusewitch G., Johnson R. Effects of high- vs moderateintensity exercise on natural killer cell activity. <em>Medicine</em> & <em>Science</em> <i>in</i> <em>Sports</em> & <em>Exercise</em>. 1993, vol.25, pp. 1126–1134.</p>
<p>Nieman D.C., Tan S.A., Lee J.W. Complement and immunoglobulin levels in athletes and sedentary controls. <em>International Journal of Sports Medicine. </em>1989, vol.10, pp. 124–128.</p>
<p>Nieman D.C., Nehlsen-Cannarella S.L. The effects of acute and chronic exercise and immunoglobulins. <em>Sports Medicine. </em>1991, vol.11, pp. 183–201.</p>
<p>Oztürk L., Pelin Z., Karadeniz D., Kaynak H., Cakar L. Effects of 48 hours sleep deprivation on human immune profile. <em>Sleep Research,</em> 1999, vol.2, pp. 107-111.</p>
<p>Petibois C., Cazorla G., Deleris G. The biological and metabolic adaptations to 12 months training in elite rowers. <em>International Journal of Sports Medicine. </em>2003, vol.24, pp. 36–42.</p>
<p>Poortmans J., Haralambie G. Biochemical changes in a 100 km run: proteins in serum and urine. <em>European</em> <i>Journal of</i> <em>Physiology</em>, 1979, vol.40, pp. 245–254.</p>
<p>Renwine L., Hauger R.L., Gilln J.C., Irwin M. Effects of sleep and sleep deprivation on interleukin-6, growth hormone, cortisol, and melatonin levels in humans. <i>Journal of Clinical</i> <em>Endocrinology</em> & <em>Metabolism. </em>2000, vol.85, pp. 3597–3603.</p>
<p>Ruiz F.S., Andersen M.L., Martins R.C., Zager A., Lopes J.D., Tufik S. Immune alterations after selective rapid eye movement or total sleep deprivation in healthy male volunteers. <em>Innate Immunity.</em> 2012, vol.18, pp. 44-54.</p>
<p>Taheri M., Arabamery M. The effect of sleep deprivation on choice reaction time and anaerobic power of college student athletes. <i>Asian Journal of Sports Medicine</i>, 2012, vol.3, pp. 15-20.</p>
<p>Tamagawa R., Lobb B., Booth R. Tolerance of shift work. <i>Applied</i> <em>Ergonomics.</em> 2007, vol.38, pp. 635–642.</p>
Downloads
Published
2014-12-28
How to Cite
1.
Saeed JF, Mirza HNK. THE EFFECT OF SLEEP DEPRIVATION ON SERUM IGG RESPONSES TO AEROBIC ACTIVITY IN COLLEGE STUDENT ATHLETES. Physical Education of Students. 2014;18(6):90-5. https://doi.org/10.15561/20755279.2014.0617
Issue
License
Copyright Holder - Author(s). more
Statistics
Abstract views: 668 / PDF downloads: 613
