Effect of training on the development of exercise-induced arterial hypoxemia in volleyball players

Keywords: desaturation, pulse oximetry, oxyhemoglobin saturation, team sports athletes


Background and Study Aim. The purpose of this study was to examine the effect of volleyball training on the development of exercise-induced arterial hypoxemia during incremental exercise in male competitive volleyball players. Material and Methods.  Eight male amateur volleyball players (age 21±1.3 years) participated in a 6-week volleyball training program three times a week in the pre-season preparatory period. Before and after the training period, all players performed an incremental treadmill test to determine maximal oxygen uptake (VO2max), and oxyhemoglobin saturation (SaO2) was continuously measured using a pulse oximeter during the test. Maximal values of minute ventilation (VEmax), respiratory exchange ratio (RERmax), ventilatory equivalent for oxygen (VE/VO2) and carbon dioxide (VE/VCO2) were determined. Exercise-induced arterial hypoxemia (EIAH) was defined as a SaO2 decreased by at least 4% (ΔSaO2≤ −4%) from resting level. Results. All the players exhibited exercise-induced arterial hypoxemia before (ΔSaO2= –8.8±3.3%) and after (ΔSaO2= –8.31.5%) the training period. SaO2 was significantly decreased from 97.6±1% at rest to 88.7±2.7% at exhaustion before the training period, and from 97.2±1.1% at rest to 88.8±2.1% at exhaustion after training period (p < 0.001). There was no significant difference in resting and lowest SaO2 values by comparison between the before and after training (p > 0.05). There were no significant changes in VO2max, VEmax, RERmax, VE/VO2 and VE/VCO2 after training period (p > 0.05). Conclusions. The results of this study showed that volleyball players with a history of anaerobic training may exhibit EIAH, but that 6-week volleyball training has no effect on the degree of exercise-induced arterial hypoxemia.


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Author Biographies

Selcen Korkmaz Eryılmaz, Cukurova University
selcen_korkmaz@yahoo.com; Department of Coaching Education, Faculty of Sport Science, Cukurova University; 01330 Balcalı, Sarıçam. Adana. Turkey.
Kerimhan Kaynak, Erciyes University
kerimhankaynak07@hotmail.com; Department of Coaching Education, Faculty of Sport Science, Erciyes University; Kayseri, Turkey.


1. Lanferdini FJ, Silva ES, Machado E, Fischer G, Peyré-Tartaruga LA. Physiological Predictors of Maximal Incremental Running Performance. Frontiers in Physiology, 2020; 11: 979.

2. Dempsey JA, Wagner PD. Exercise induced arterial hypoxemia. Journal of applied physiology, 1999; 87:1997–2006.

3. Powers SK, Lawler J, Dempsey JA, Dodd S, Landry G. Effects of incomplete pulmonary gas exchange on VO2max. Journal of Applied Physiology. 1989; 66(6):2491–5.

4. Constantini K, Tanner DA, Gavin TP, Harms CA, Stager JM, Chapman RF. Prevalence of exercise-induced arterial hypoxemia in distance runners at sea level. Medicine and Science in Sports and Exercise, 2017; 49:948–954.

5. Dominelli PB, Molgat-Seon Y, Griesdale DEG, Peters CM, Blouin JS, Sekhon M., et al. Exercise-induced quadriceps muscle fatigue in men and women: effects of arterial oxygen content and respiratory muscle work. The Journal of Physiology, 2017; 595(15): 5227–5244.

6. Harms CA, McClaran SR, Nickele GA, Pegelow DF, Nelson WB, Dempsey JA. Effect of exercise-induced arterial O2 desaturation on VO2max in women. Medicine and Science in Sports and Exercise. 2000; 32(6):1101–8.

7. Ohya T, Yamanaka R, Ohnuma H, Hagiwara M, Suzuki Y. Hyperoxia extends time to exhaustion during high-intensity intermittent exercise: a randomized, crossover study in male cyclists. Sports Medicine-Open, 2016; 2(1): 34.

8. Hopkins SR, McKenzie DC, Schoene RB, Glenny RW, Robertson HT. Pulmonary gas exchange during exercise in athletes. I. Ventilation-perfusion mismatch and diffusion limitation. Journal of Applied Physiology, 1994; 77(2), 912–917.

9. Dominelli PB, Sheel AW. Exercise-induced arterial hypoxemia; some answers, more questions. Applied Physiology, Nutrition, and Metabolism, 2019; 44(6):571–579.

10. Granger EA, Cooper TK, Hopkins SR, McKenzie DC, Dominelli P. Peripheral chemoresponsiveness during exercise in male athletes with exercise‐induced arterial hypoxaemia. Experimental Physiology. 2020; 44(6);571- 579.

11. Williams JH, Powers SK, Stuart MK. Hemoglobin desaturation in highly trained athletes during heavy exercise. Medicine and Science in Sports and Exercise. 1986; 18:168–73.

12. Miyachi M, Katayama K. Effects of maximal interval training on arterial oxygen desaturation and ventilation during heavy exercise. The Japanese Journal of Physiology, 1999; 49(5), 401–407.

13. Korkmaz Eryılmaz S, Polat M. Exercise-induced arterial hypoxemia in aerobic and anaerobic trained athletes during incremental exercise. Physical Education of Students, 2018; 22(2): 99–103.

14. Mucci P, Blondel N, Fabre C, Nourry C, Berthoin S. Evidence of exercise-induced O2 arterial desaturation in non-elite sportsmen and sportswomen following high-intensity interval-training. International Journal of Sports Medicine, 2004; 25(01):6–13.

15. Dominelli PB, Foster GE, Dominelli GS, Henderson WR, Koehle MS, McKenzie DC, et al. Exercise-induced arterial hypoxemia is unaffected by intense physical training: a case report. Applied Physiology, Nutrition, and Metabolism, 2014; 39(2):266–269.

16. Thalheimer W, Cook S. How to calculate effect sizes from published research articles: A simplified methodology. Available at: http://work learning.com/effect_sizes.htm. Accessed on January 11, 2016.

17. Powers SK, Dodd S, Lawler J, Landry G, Kirtley M, McKnight T, et al. Incidence of exercise induced hypoxemia in elite endurance athletes at sea level. European Journal of Applied Physiology, 1988; 58:298–302.

18. Galy O, Le Gallais D, Hue O, Boussana A, Prefaut C. Is Exercise-induced arterial hypoxemia in triathletes dependent on exercise modality?. International Journal of Sports Medicine, 2005; 26(9):719–726.

19. Rasmussen J, Hanel B, Diamant B, Secher NH. Muscle mass effect on arterial desaturation after maximal exercise. Medicine and Science in Sports and Exercise, 1991; 23:1349–1352.

20. Tanner DA, Duke JW, Stager JM. Ventilatory patterns differ between maximal running and cycling. Respiratory Physiology & Neurobiology, 2014; 191, 9–16.

21. Dempsey JA, Hanson PG, Henderson KS. Exercise-induced arterial hypoxaemia in healthy human subjects at sea level. Journal of Physiology. 1984; 355:161–175.

22. Martin D, Powers S, Cicale M, Collop N, Huang D, Criswell D. Validity of pulse oximetry during exercise in elite endurance athletes. Journal of Applied Physiology, 1992; 72(2):455–458.

23. Mollard P, Bourdillon N, Letournel M, Herman H, Gibert S, Pichon A, et al. Validity of arterialized earlobe blood gases at rest and exercise in normoxia and hypoxia. Respiratory Physiology Neurobiology, 2010; 172(3):179–183.

24. Brown DD, Knowlton RG, Sanjabi PB, Szurgot BT. Re-examination of the incidence of exercise-induced hypoxaemia in highly trained subjects. British Journal Sports Medicine, 1993; 27(3):167–70.

25. Gaston AF, Durand F, Roca E, Doucende G, Hapkova I, Subirats E. Exercise-induced hypoxaemia developed at sea-level influences responses to exercise at moderate altitude. PLoS One, 2016; 11(9): e0161819.

26. Alis R, Sanchis-Gomar F, Ferioli D, La Torre A, Blesa JR, Romagnoli M. Exercise Effects on Erythrocyte Deformability in Exercise-induced Arterial Hypoxemia. International Journal of Sports Medicine, 2015; 36(4):286–91.

27. Rice AJ, Scroop GC, Gore CJ, Thornton AT, Chapman MJ, Greville HW, et al. Exercise-induced hypoxaemia in highly trained cyclists at 40% peak oxygen uptake. European Journal of Applied Physiology, 1999; 79(4):353–359.

28. Martin B, Sparks K, Zwıllıch C, Weıl J. Low exercise ventilation in endurance athletes. Medicine and Science in Sports, 1979; 11(2):181–185.

29. Miyachi M, Tabata I. Relationship between arterial oxygen desaturation and ventilation during maximal exercise. Journal of Applied Physiology, 1992; 73(6):2588–2591.

30. Hakkinen K. Changes in physical fitness profile in female volleyball players during the competitive season. Journal of Sport Medicine and Physical Fitness, 1993; 33(3):223–232.

31. Powers SK, Dodd S, Woodyard J, Beadle RE, Church G. Haemoglobin saturation during incremental arm and leg exercise. British Journal Sports Medicine, 1984; 18(3):212–216.

32. Powers SK, Martin D, Cicale M, Collop N, Huang D, Criswell D. Exercise-induced hypoxemia in athletes: role of inadequate hyperventilation. European Journal of Applied Physiology and Occupational Physiology, 1992; 65(1):37–42.
How to Cite
Korkmaz Eryılmaz S, Kaynak K. Effect of training on the development of exercise-induced arterial hypoxemia in volleyball players. Physical education of students. 2020;24(6):312-8. https://doi.org/10.15561/20755279.2020.0602