TY - JOUR AU - Sokolenko, Vadym L. AU - Sokolenko, Svitlana V. PY - 2020/10/30 Y2 - 2024/03/29 TI - Parameters of lipid and oxidative-antioxidant status in persons aged 18-23 from radiation-contaminated areas under conditions of moderate physical activity JF - Physical Education of Students JA - PES VL - 24 IS - 5 SE - Articles DO - 10.15561/20755279.2020.0506 UR - https://sportedu.org.ua/index.php/PES/article/view/1257 SP - 293-303 AB - <p><em>Background and Study Aim</em><em>. </em>There is a significant amount of data on the stressful effects of exercise, which contain conflicting results. Some publications testify to the adaptive processes and the benefits of optimized exercise for various physiological systems, some deny such an effect. Much controversial is the question of combination the physical exercises of different intensity with other stressors. The purpose of the study: to analyze the parameters of lipid metabolism and oxidative-antioxidant system in persons aged 18-23 who lived in territories with different radioecological status, under conditions of moderate physical activity during exercise.</p><p><em>Material and Methods</em><em>. </em>There were examined 50 students from relatively ecologically clean areas (control group) and 50 students from the IV radiation zone (experimental group). The radiation zone is selected by the dosimetry of soil contamination with <sup>137</sup>Cs isotopes after the Chornobyl catastrophe. Age of the examined is 18-23 years. Within the framework of the experimental group there were formed two subgroups: the main group for physical training classes (without signs of morphological-functional disorders) and the group for therapeutic physical training classes (TPTC, persons with signs of vegetative-vascular dystonia syndrome). For the control and experimental main group, classes contained all the planned exercises due to the standard curriculum. The program included a combination of aerobic and strength exercises of moderate intensity. For students with signs of vegetative-vascular dystonia, teachers used specially designed therapeutic exercise complexes. The first analysis of parameters was carried out the day before physical training classes, the second one – immediately after the class.</p><p><em>Results</em><em>. </em>Higher levels of total cholesterol and its lipoprotein fractions (LDL-C and HDL-C), triglycerides, oxidative stress index are detected in the experimental group compared to the control group. At the same time lower levels of sulfhydryl groups (SH) were marked. The absence of statistically significant changes in the analyzed parameters in the control group and the experimental therapeutic group after physical exercises is shown in the study. There were evident tendencies of ceruloplasmin level increase in the control along with the absence of such trends in persons with signs of vegetative-vascular dystonia syndrome. This led to the formation of a significant difference between groups for this antioxidant. There is a significant increase in cortisol level and oxidative stress index in the main group of students from radiation contaminated areas.</p><p><em>Conclusions</em><em>. </em>Potentiation of various stress factors in persons who experienced the prolonged exposure to Chornobyl accident reduces the adaptive potential of homeostatic systems. This eliminates the optimization of lipid metabolism and oxidative-antioxidant system through moderate exercise. Exercise therapy does not cause a pronounced stress effect.</p> ER -